/ Dictionary / Index P profanation: Meaning and Definition of Find definitions for: prof•a•na•tion Pronunciation: (prof"u-nā'shun), [key] — n. the act of profaning; desecration; defilement; debasement. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: profanation (Thesaurus) profamily profanatory Related Content Daily Word Quiz: candor Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language