/ Dictionary / Index P progeria: Meaning and Definition of Find definitions for: pro•ge•ri•a Pronunciation: (prō-jēr'ē-u), [key] — n. Pathol. a rare congenital abnormality characterized by premature and rapid aging, the affected individual appearing in childhood as an aged person and having a shortened life span. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: progeria (Thesaurus) progeny progestational Related Content Daily Word Quiz: blanch Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language