/ Dictionary / Index P proliferation: Meaning and Definition of Find definitions for: pro•lif•er•a•tion Pronunciation: (pru-lif"u-rā'shun), [key] — n. the growth or production of cells by multiplication of parts. a rapid and often excessive spread or increase: nuclear proliferation. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: proliferation (Thesaurus) proliferate proliferous Related Content Daily Word Quiz: frugal Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language