/ Dictionary / Index P protease: Meaning and Definition of Find definitions for: pro•te•ase Pronunciation: (prō'tē-ās", -āz"), [key] — n. Biochem. any of a group of enzymes that catalyze the hydrolytic degradation of proteins or polypeptides to smaller amino acid polymers. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: protease (Thesaurus) protean protect Related Content Daily Word Quiz: deleterious Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language