/ Dictionary / Index P proteoglycan: Meaning and Definition of Find definitions for: pro•te•o•gly•can Pronunciation: (prō"tē-ō-glī'kan), [key] — n. Biochem. a macromolecule composed of a polysaccharide joined to a polypeptide and forming the ground substance of connective tissue. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. protensive proteolysis Related Content Daily Word Quiz: opulent Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language