/ Dictionary / Index P Prozac: Meaning and Definition of Find definitions for: Pro•zac Pronunciation: (prō'zak), [key] a drug that inhibits the release of serotonin and is used chiefly as an antidepressant. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: prozac (Thesaurus) proxy statement prp. Related Content Daily Word Quiz: pugilist Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language