/ Dictionary / Index P pupfish: Meaning and Definition of Find definitions for: pup•fish Pronunciation: (pup'fish"), [key] — pl. -fish, -fish•es. any of several tiny, stout killifishes of the genus Cyprinodon, inhabiting marshy waters in arid areas of western North America: several species are endangered. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. pupate pupil Related Content Daily Word Quiz: paradox Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language