/ Dictionary / Index P pustule: Meaning and Definition of Find definitions for: pus•tule Pronunciation: (pus'chool), [key] — n. a small elevation of the skin containing pus. any pimplelike or blisterlike swelling or elevation. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: pustule (Thesaurus) pustulation pustulous Related Content Daily Word Quiz: cygnet Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language