/ Dictionary / Index R Rufen: Meaning and Definition of Find definitions for: Ru•fen Pronunciation: (r'fun), [key] — Pharm., Trademark. Pharm.,Trademark. a brand of ibuprofen. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. rueful rufescent Related Content Daily Word Quiz: placid Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language