/ Dictionary / Index S sain: Meaning and Definition of Find definitions for: sain Pronunciation: (sān), [key] — v.t. Archaic. to make the sign of the cross on, as for protection against evil influences. to bless. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. Saimaa sainfoin Related Content Daily Word Quiz: neologism Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language