/ Dictionary / Index S sanctum sanctorum: Meaning and Definition of Find definitions for: sanc'tum sanc•to'rum Pronunciation: (sangk-tôr'um, -tōr'-), [key] the holy of holies of the Biblical tabernacle and the Temple in Jerusalem. sanctum (def. 2). Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. sanctum Sanctus Related Content Daily Word Quiz: procrastinate Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language