/ Dictionary / Index S sanguine: Meaning and Definition of Find definitions for: san•guine Pronunciation: (sang'gwin), [key] — adj. cheerfully optimistic, hopeful, or confident: a sanguine disposition; sanguine expectations. reddish; ruddy: a sanguine complexion. (in old physiology) having blood as the predominating humor and consequently being ruddy-faced, cheerful, etc. bloody; sanguinary. blood-red; red. a reddish-purple tincture. —n. a red iron-oxide crayon used in making drawings. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: sanguine (Thesaurus) sanguinary sanguineous Related Content Daily Word Quiz: secular Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language