/ Dictionary / Index S sarcomere: Meaning and Definition of Find definitions for: sar•co•mere Pronunciation: (sär'ku-mēr"), [key] — n. Biol. any of the segments of myofibril in striated muscle fibers. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: sarcomere (Thesaurus) sarcomatosis sarcophagous Related Content Daily Word Quiz: designate Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language