/ Dictionary / Index S sedative: Meaning and Definition of Find definitions for: sed•a•tive Pronunciation: (sed'u-tiv), [key] — adj. tending to calm or soothe. allaying irritability or excitement; assuaging pain; lowering functional activity. —n. a sedative drug or agent. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: sedative (Thesaurus) sedation Seddon Related Content Daily Word Quiz: endear Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language