/ Dictionary / Index S self-interest: Meaning and Definition of Find definitions for: self-in•ter•est Pronunciation: (self"in'tur-ist, -trist, self'-), [key] — n. regard for one's own interest or advantage, esp. with disregard for others. personal interest or advantage. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: self-interest (Thesaurus) self-insurer selfish Related Content Daily Word Quiz: paradox Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language