/ Dictionary / Index S serene: Meaning and Definition of Find definitions for: se•rene Pronunciation: (su-rēn'), [key] — adj. calm, peaceful, or tranquil; unruffled: a serene landscape; serene old age. clear; fair: serene weather. (usually cap.) most high or august (used as a royal epithet, usually prec. by his, your, etc.): His Serene Highness. —n. serenity; tranquillity. a clear or tranquil expanse of sea or sky. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: serene (Thesaurus) serendipity berry Serengeti Related Content Daily Word Quiz: paradox Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language