/ Dictionary / Index S seronegative: Meaning and Definition of Find definitions for: se•ro•neg•a•tive Pronunciation: (sēr"ō-neg'u-tiv), [key] — adj. Med. showing no significant level of serum antibodies, or other immunologic marker in the serum, that would indicate previous exposure to the infectious agent being tested. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. serology seropositive Related Content Daily Word Quiz: paradox Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language