/ Dictionary / Index S serum: Meaning and Definition of Find definitions for: se•rum Pronunciation: (sēr'um), [key] — pl. se•rums, se•ra the clear, pale-yellow liquid that separates from the clot in the coagulation of blood; blood serum. See any watery animal fluid. the thin, clear part of the fluid of plants. milk whey. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: serum (Thesaurus) sertularian serum albumin Related Content Daily Word Quiz: spectral Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language