/ Dictionary / Index S shoot-up: Meaning and Definition of Find definitions for: shoot-up Pronunciation: (sht'up"), [key] — n. Slang. an act or instance of injecting an addictive drug intravenously. shootout (def. 1). Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: shoot-up (Thesaurus) shoot the chutes shop Related Content Daily Word Quiz: sinister Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language