/ Dictionary / Index S Sicily: Meaning and Definition of Find definitions for: Sic•i•ly Pronunciation: (sis'u-lē), [key] — n. an island in the Mediterranean, constituting a region of Italy, and separated from the SW tip of the mainland by the Strait of Messina: largest island in the Mediterranean. 4,909,996; 9924 sq. mi. (25,705 sq. km). Cap.: Palermo. Italian,Ancient, Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: sicily (Thesaurus) Sicilies, Two sick Related Content Daily Word Quiz: endear Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language