/ Dictionary / Index S side effect: Meaning and Definition of Find definitions for: side' effect" Pronunciation: [key] any effect of a drug, chemical, or other medicine that is in addition to its intended effect, esp. an effect that is harmful or unpleasant. any accompanying or consequential and usually detrimental effect: the side effects of air pollution. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. side drum side-glance Related Content Daily Word Quiz: arboreal Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language