/ Dictionary / Index S Siena: Meaning and Definition of Find definitions for: Sie•na Pronunciation: (sē-en'uIt.sye'nä), [key] — n. a city in Tuscany, in central Italy, S of Florence: cathedral. 64,745. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. Siem Reap Sienese Related Content Daily Word Quiz: reiterate Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language