/ Dictionary / Index S significance: Meaning and Definition of Find definitions for: sig•nif•i•cance Pronunciation: (sig-nif'i-kuns), [key] — n. importance; consequence: the significance of the new treaty. meaning; import: The familiar place had a new significance for her. the quality of being significant or having a meaning: to give significance to dull chores. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: significance (Thesaurus) signifiant* significance level Related Content Daily Word Quiz: neologism Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language