/ Dictionary / Index S significancy: Meaning and Definition of Find definitions for: sig•nif•i•can•cy Pronunciation: (sig-nif'i-kun-sē), [key] — pl. -cies. significance. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. significance level significant Related Content Daily Word Quiz: neologism Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language