/ Dictionary / Index S significant digits: Meaning and Definition of Find definitions for: signif'icant dig'its Pronunciation: [key] — Math. Math. all the nonzero digits of a number and the zeros that are included between them or that are final zeros and signify accuracy:Also called The significant digits of 0.01230 are 1, 2, 3, and the final 0, which signifies accuracy to five places. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. significant significant other Related Content Daily Word Quiz: neologism Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language