/ Dictionary / Index S Sikeston: Meaning and Definition of Find definitions for: Sikes•ton Pronunciation: (sīk'stun), [key] — n. a city in SE Missouri. 17,431. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. siker Sikh Related Content Daily Word Quiz: dissonant Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language