/ Dictionary / Index S single-cross: Meaning and Definition of Find definitions for: sin•gle-cross Pronunciation: (sing'gul-krôs', -kros'), [key] — n. Genetics. a cross between two inbred lines. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. single combat single cut Related Content Daily Word Quiz: resilient Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language