/ Dictionary / Index S skin reaction: Meaning and Definition of Find definitions for: skin' reac"tion Pronunciation: [key] an irritation or inflammation of the skin due to an allergy or infection, brought about by natural means or by a skin test. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. skin-pop skin search Related Content Daily Word Quiz: procrastinate Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language