/ Dictionary / Index S South San Francisco: Meaning and Definition of Find definitions for: South' San" Francis'co Pronunciation: [key] a city in central California. 49,393. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. South Salt Lake South Sea Islands Related Content Daily Word Quiz: cautious Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language