/ Dictionary / Index S spandex: Meaning and Definition of Find definitions for: span•dex Pronunciation: (span'deks), [key] — n. Chem. a synthetic fiber composed of a long-chain polymer, used chiefly in the manufacture of garments to add elasticity. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: spandex (Thesaurus) Spandau spandrel Related Content Daily Word Quiz: neologism Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language