/ Dictionary / Index S spherule: Meaning and Definition of Find definitions for: spher•ule Pronunciation: (sfer'l, -yl, sfēr'-), [key] — n. a small sphere or spherical body. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: spherule (Thesaurus) spheroplast spherulite Related Content Daily Word Quiz: paradox Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language