/ Dictionary / Index S spireme: Meaning and Definition of Find definitions for: spi•reme Pronunciation: (spī'rēm), [key] — n. Cell Biol. the threadlike chromatin of a cell nucleus, present during early meiosis or mitosis. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. spirelet Spires Related Content Daily Word Quiz: paradox Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language