/ Dictionary / Index S spleenful: Meaning and Definition of Find definitions for: spleen•ful Pronunciation: (splēn'ful), [key] — adj. full of or displaying spleen. ill-humored; irritable or peevish; spiteful; splenetic. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. spleen spleenwort Related Content Daily Word Quiz: neologism Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language