/ Dictionary / Index S splen-: Meaning and Definition of Find definitions for: splen- Pronunciation: [key] var. ofbefore a vowel: splenectomy. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. spleeny splendent Related Content Daily Word Quiz: neologism Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language