/ Dictionary / Index S sputum: Meaning and Definition of Find definitions for: spu•tum Pronunciation: (spy'tum), [key] — pl. -ta matter, as saliva mixed with mucus or pus, expectorated from the lungs and respiratory passages. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: sputum (Thesaurus) sputtering Spuyten Duyvil Creek Related Content Daily Word Quiz: endear Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language