/ Dictionary / Index S St. Charles: Meaning and Definition of Find definitions for: St. Charles Pronunciation: [key] a city in E Missouri, on the Missouri River. 37,379. a town in NE Illinois. 17,492. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. St. Catharines St. Christopher Related Content Daily Word Quiz: ounterfeit Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language