/ Dictionary / Index S steric hindrance: Meaning and Definition of Find definitions for: ster'ic hin'drance Pronunciation: [key] — Chem. Chem. the prevention or retardation of inter- or intramolecular interactions as a result of the spatial structure of a molecule. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. steric sterigma Related Content Daily Word Quiz: endear Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language