/ Dictionary / Index S substructure: Meaning and Definition of Find definitions for: sub•struc•ture Pronunciation: (sub-struk'chur, sub'struk"-), [key] — n. a structure forming the foundation of a building or other construction. the foundations, piers, and abutments upon which the trusses or girders of the spans of a bridge rest. any basic structure or organization. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: substructure (Thesaurus) substruction subsulfate Related Content Daily Word Quiz: neologism Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language