/ Dictionary / Index S surefire: Meaning and Definition of Find definitions for: sure•fire Pronunciation: (shoor'fīr", shûr'-), [key] — adj. sure to work; foolproof: a surefire moneymaking scheme. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. sure-enough surefooted Related Content Daily Word Quiz: cetacean Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language