/ Dictionary / Index S sure thing: Meaning and Definition of Find definitions for: sure' thing' Pronunciation: [key] something that is or is supposed to be a certain success, as a bet or a business venture: He thinks that real estate is a sure thing. something assured; certainty: It's a sure thing that he'll refuse to cooperate. surely; for sure; O.K.; roger (often used as an interjection). Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. Sûreté surety Related Content Daily Word Quiz: paradox Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language