/ Dictionary / Index S sysop: Meaning and Definition of Find definitions for: sys•op Pronunciation: (sis'op"), [key] — n. Computers Informal. a person who operates a computer bulletin board. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. sys- syssarcosis Related Content Daily Word Quiz: neologism Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language