/ Dictionary / Index S systemic: Meaning and Definition of Find definitions for: sys•tem•ic Pronunciation: (si-stem'ik), [key] — adj. of or pertaining to a system. pertaining to or affecting the body as a whole. pertaining to or affecting a particular body system. (of a pesticide) absorbed and circulated by a plant or other organism so as to be lethal to pests that feed on it. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: systemic (Thesaurus) systematology systemic circulation Related Content Daily Word Quiz: endear Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language