/ Dictionary / Index T topectomy: Meaning and Definition of Find definitions for: to•pec•to•my Pronunciation: (tu-pek'tu-mē), [key] — pl. -mies. excision of part of the cerebral cortex for the relief of unmanageable pain or esp. as a treatment for certain mental disorders. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. tope topee Related Content Daily Word Quiz: wizened Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language