/ Dictionary / Index T twerp: Meaning and Definition of Find definitions for: twerp Pronunciation: (twûrp), [key] — n. Slang. an insignificant or despicable fellow: Her father thinks her boyfriend is just a twerp. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: twerp (Thesaurus) 'twere Twi Related Content Daily Word Quiz: clairvoyant Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language