/ Dictionary / Index U unsex: Meaning and Definition of Find definitions for: un•sex Pronunciation: (un-seks'), [key] — v.t. to deprive of sexual power; render impotent or frigid; spay or castrate. to deprive (oneself or another) of the proper or appropriate character and qualities of one's sex, as by unnatural conduct. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: unsex (Thesaurus) unsew unshackle Related Content Daily Word Quiz: inutiae Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language