/ Dictionary / Index U uptake: Meaning and Definition of Find definitions for: up•take Pronunciation: (up'tāk"), [key] — n. apprehension; understanding or comprehension; mental grasp: quick on the uptake. an act or instance of taking up; a lifting: the uptake of fertilizer by machines. Also calleda pipe or passage leading upward from below, as for conducting smoke or a current of air. absorption. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: uptake (Thesaurus) upsy-daisy uptalk Related Content Daily Word Quiz: fabricate Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language