/ Dictionary / Index V vaccinia: Meaning and Definition of Find definitions for: vac•cin•i•a Pronunciation: (vak-sin'ē-u), [key] — n. a variant of the cowpox virus that became established in vaccines derived from cowpox-inoculated humans. an acute infection caused by inoculation with vaccinia virus as a prophylactic against smallpox, characterized by localized pustular eruptions. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: vaccinia (Thesaurus) vaccine point vaccinization Related Content Daily Word Quiz: banshee Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language