/ Dictionary / Index V vesicle: Meaning and Definition of Find definitions for: ves•i•cle Pronunciation: (ves'i-kul), [key] — n. a small sac or cyst. a small bladderlike cavity, esp. one filled with fluid. a circumscribed elevation of the epidermis containing serous fluid; blister. a small, usually spherical cavity in a rock or mineral, formed by expansion of a gas or vapor before the enclosing body solidified. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: vesicle (Thesaurus) vesicatory vesicular Related Content Daily Word Quiz: perspicacious Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language