| First Round—Atlanta | Duke 70, Southern 54 |
| George Washington 88, UNC-Wilmington 85 |
| Syracuse 58, Texas A&M 66 |
| Louisiana State 80, Iona 64 |
| West Virginia 64, Southern Illinois 46 |
| Iowa 63, Northwest State 64 |
| California 52, North Carolina State 58 |
| Texas 60, Pennsylvania 52 |
| First Round—Washington, DC | Connecticut 72, Albany 59 |
| Kentucky 69, Univ. of Alabama-Birmingham 64 |
| Washington 75, Utah State 61 |
| Illinois 78, Air Force 69 |
| Michigan State 65, George Mason 75 |
| Univ. of North Carolina 69, Murray State 65 |
| Wichita State 86, Seton Hall 66 |
| Tennessee 63, Winthrop 61 |
| First Round—Minneapolis | Villanova 58, Monmouth 45 |
| Arizona 94, Wisconsin 75 |
| Nevada 79, Montana 87 |
| Boston College 88, Pacigic 76 |
| Oklahoma 74, Wisconsin-Milwaukee 82 |
| Florida 76, South Alabama 50 |
| Georgetown 54, North Iowa 49 |
| Ohio State 70, Davidson 62 |
| First Round—Oakland | Memphis 94, Oral Roberts 78 |
| Arkansas 55, Bucknell 59 |
| Pittsburgh 79, Kent State 64 |
| Kansas 73, Bradley 77 |
| Indiana 87, San Diego State 83 |
| Gonzaga 79, Xavier 75 |
| Marquette 85, Alabama 90 |
| UCLA 78, Belmont 44 |
| Second Round—Atlanta | Duke 74, George Washington 61 |
| Texas A&M 57, Louisiana State 58 |
| West Virginia 67, Northwest State 54 |
| North Carolina State 54, Texas 75 |
| Second Round—Washington, DC | Connecticut 87, Kentucky 83 |
| Washington 67, Illinois 64 |
| George Mason 65, Univ. of North Carolina 60 |
| Wichita State 80, Tennessee 73 |
| Second Round—Minneapolis | Villanova 82, Arizona 78 |
| Montana 56, Boston College 69 |
| Wisconsin-Milwaukee 60, Florida 82 |
| Georgetown 70, Ohio State 52 |
| Second Round—Oakland | Memphis 72, Bucknell 56 |
| Pittsburgh 66, Bradley 72 |
| Indiana 80, Gonzaga 90 |
| Alabama 59, UCLA 62 |
| Third Round—Atlanta | Duke 54, Louisiana State 62 |
| West Virginia 71, Texas 74 |
| Third Round—Washington, DC | Connecticut 98, Washington 92 |
| George Mason 63, Wichita State 55 |
| Third Round—Minneapolis | Villanova 60, Boston College 59 |
| Florida 57, Georgetown 53 |
| Third Round—Oakland | Memphis 80, Bradley 64 |
| Gonzaga 71, UCLA 73 |
| Regional Finals | Atlanta—Louisiana State 70, Texas 60 |
| Washington, DC—Connecticut 84, George Mason 86 |
| Minneapolis—Villanova 62, Florida 75 |
| Oakland—Memphis 45, UCLA 50 |
| Final Four | (April 1, 2006, Indianapolis, Ind.) |
| Louisiana State 45, UCLA 59 |
| George Mason 58, Florida 73 |
| National Final | (April 3, 2006, Indianapolis, Inc..) |
| UCLA 57, Florida 73 |
