/ Thesaurus / M Synonyms of megacolon Find synonyms for: Noun1. megacolon, colonusage: an abnormal enlargement of the colon; can be congenital (as in Hirschsprung's disease) or acquired (as when children refuse to defecate)WordNet 3.0 Copyright © 2006 by Princeton University. All rights reserved. Related Content Daily Word Quiz: foliage Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language